Home -> Papers


Citations = >200 – h-index = 8

Cancer Immunology

1. KARANIKAS V, ZAMANAKOU M, SOUKOU F, KERENIDI T, TSOUGOS I, THEODOROU K, GEORGOULIAS P, GOURGOULIANIS KI, GERMENIS AE. Cytolytic T-cell response against Epstein-Barr virus in lung cancer patients and healthy subjects. Viral Immunology (submitted)
2. KARANIKAS V, ZAMANAKOU M, SOUKOU F, KERENIDI T, GOURGOULIANIS KI, GERMENIS AE. Frequency and function of naturally occurring cytolytic CD8+ T cell precursors against multiple tumor antigen peptides in lung cancer patients and healthy individuals. Immunology & Cell Biology 2010 (in press)
3. GERMENIS AE, KARANIKAS V. Cord blood lymphocytes combating immunosenescence of anti-tumor lymphocytes. Journal of Reproductive Immunology 2010 (in press)
4. KARANIKAS V, GERMENIS AE. Tumor specific CD8+ T cells in patients with lung cancer and healthy individuals. Journal of BUON 2009, 14(Suppl 1):S153-S157 (seminar article)
5. AVRAMOULI A, TSOCHAS S, MANDALA E, KATODRITOU E, IOANNOU M, RITIS K, SPELETAS M. Methylation status of RASSF1A in patients with chronic myeloid leukemia. Leukemia Research 2009, 33:1130-1132
6. KARANIKAS V, KHALIL S, KERENIDI T, GOURGOULIANIS KI, GERMENIS AE. Anti-survivin antibody responses in lung cancer. Cancer Letters 2009, 282:159-166
7. KARANIKAS V, SOUKOU F, KALALA F, KERENIDI T, GRAMMOUSTIANOU ES, GOURGOULIANIS KI, GERMENIS AE. Baseline levels of CD8+ T cells against survivin and survivin-2B in the blood of lung cancer patients and cancer-free individuals. Clinical Immunology 2008, 129:230-240
8. KARANIKAS V, SPELETAS M, ZAMANAKOU M, KALALA F, LOULES G, KERENIDI T, GOURGOULIANIS KI, GERMENIS AE. Foxp3 expression in human cancer cells. Journal of Translational Medicine 2008, 6:19
9. KARANIKAS V, TSOHAS S, BOUKAS K, KERENIDI T, NAKOU M, DAHABREH J, POULARAKIS T, GOURGOULIANIS KI, GERMENIS AE. Co-expression patterns of tumor-associated antigen genes by non-small cell lung carcinomas: Implications for immunotherapy. Cancer Biology & Therapy 2008, 7:345-352
10. SPELETAS M, VYZANTIADIS T-A, KALALA F, PLASTIRAS D, KOKOVIADOU K, ANTONIADIS A, KORANTZIS I. Pneumonia caused by Candida krusei and Candida glabrata in a patient with chronic myeloid leukemia receiving imatinib mesylate treatment. Medical Mycology 2008, 46:259-263 (case report)
11. KARANIKAS V ZAMANAKOU M, KERENIDI T, DAHABREH J, HEVAS Α, NAKOU Μ, GOURGOULIANIS ΚΙ, GERMENIS AΕ. Indoleamine 2,3-dioxygenase (IDO) expression in lung cancer. Cancer Biology & Therapy 2007, 6:1258-1262
12. ZAMANAKOU M, GERMENIS A, KARANIKAS V. Tumour immune escape mediated by indoleamine 2,3-dioxygenase. Immunology Letters 2007, 111:69-75 (review)
13. SPELETAS M, LIADAKI K, KALALA F, DAIOU C, KATODRITOU E, MANDALA E, KORANTZIS I, RITIS K, ZINTZARAS E, GERMENIS AE. TLR4 single nucleotide polymorphisms and thrombosis risk in patients with myeloproliferative disorders. Thrombosis Research 2008, 122:27-32
14. GERMENIS AE, KARANIKAS V. Immunoepigenetics: The unseen side of cancer immunoediting. Immunology & Cell Biology 2007, 85:55-59 (theoretical article)
15. PETRIDOU ET, CHAVELAS C, DIKALIOTI SK, DESSYPRIS N, TERZIDIS A, NIKOULIS DI, MARKOPOULOS C, PAPADIAMANTIS Y, GERMENIS AE. Breast cancer risk in relation to most prevalent IgE specific antibodies: a case control study in Greece. Anticancer Research 2007, 27(3B):1709-1713
16. GERMENIS AE, KARANIKAS V, GOURGOULIANIS KI. Lung cancer: Immunosurveillance, immunoediting or immunoepigenetics? Pneumon 2005, 18:291-297 (special article)

Molecular Immunology – Immunodeficiencies

17. SPELETAS M, BOUKAS K, PAPADOPOULOU-ALATAKI E, TSITSAMI E, GERMENIS AE. Hereditary angioedema in Greek families caused by novel and recurrent mutations. Human Immunology 2009, 70:925-929
18. LOULES G, KALALA F, GIANNAKOULAS N, PAPADAKIS E, MATSOUKA P, SPELETAS M. FIP1L1-PDGFRA molecular analysis in the differential diagnosis of eosinophilia. BMC Blood Disorders 2009, 9:1
19. KAMBAS K, MITROULIS I, KOURTZELIS I, CHRYSANTHOPOULOU A, SPELETAS M, RITIS K. Fast and reliable mutation detection of the complete exon 11-15 JAK2 coding region using non-isotopic RNase cleavage assay (NIRCA). European Journal of Haematology 2009, 83:215-219
20. SPELETAS M, KIOUMI A, LOULES G, KATODRITOU E, TSITOURIDIS J, HYTIROGLOU P, CHRISTAKIS J, GERMENIS AE. Analysis of SLC40A1 (ferroportin 1) gene at mRNA level reveals rapidly the causative mutations in patients with hemochromatosis type IV. Blood Cells, Molecules and Diseases 2008, 40:353-359
21. DANIIL Z, KARETSI E, ZAKYNTHINOS E, BAKRATSI E, KALALA F, GOURGOULIANIS KI. Pulmonary arterial hypertension in a patient with common variable immunodeficiency and unilateral bronchiectasis: Successful treatment with iloprost. European Journal of Internal Medicine 2007, 18:333-335 (case report)

Respiratory Immunology

22. SPELETAS M, MERENTITI V, KOSTIKAS K, LIADAKI K, MINAS M, GOURGOULIANIS K, GERMENIS AE. Increased risk for COPD development in smokers with TLR4-T399I polymorphism. Journal of Developmental Immunology 2009;2009:260286
23. KOUTSOKERA A, KIROPOULOS TS, NIKOULIS DJ, DANIIL ZD, TSOLAKI V, TANOU K, PAPAIOANNOU AI, GERMENIS A, GOURGOULIANIS KI, KOSTIKAS K. Clinical, functional and biochemical changes during recovery from COPD exacerbations. Respiratory Medicine 2009, 103:919-926
24. PAPAIOANNOU AI, MAZIOTI A, KIROPOULOS T, TSILIONI I, KOUTSOKERA A, TANOU K, NIKOULIS DJ, GEORGOULIAS P, ZAKYNTHINOS E, GOURGOULIANIS KI, KOSTIKAS K. Systemic and airway inflammation and the presence of emphysema in patients with COPD. Respiratory Medicine 2009 (in press)
25. KIROPOULOS TS, KOSTIKAS K, OIKONOMIDI S, TSILIONI I, NIKOULIS D, GERMENIS A, GOURGOULIANIS KI. Acute phase markers for the differentiation of infectious and malignant pleural effusions. Respiratory Medicine 2007, 101:910-918
26. METSIOS GS, FLOURIS AD, JAMURTAS TZ, CARRILLO AE, KOURETAS D, GERMENIS AE, GOURGOULIANIS K, KIROPOULOS T, TZATZARAKIS MN, TSATSAKIS AM, KOUTEDAKIS Y. A brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion. Journal of Clinical Endocrinology and Metabolism 2007, 92:208-211
27. TSOUTSOU PG, GOURGOULIANIS KI, PETINAKI E, GERMENIS A, TSOUTSOU AG, MPAKA M, EFREMIDOU S, MOLYVDAS P-A. Cytokine levels in the sera of patients with idiopathic pulmonary fibrosis. Pulmonary Medicine 2006, 100:938-945
28. KADITIS AG, ALEXOPOULOS, EI, KALAMPOUKA E, KOSTADIMA E, ANGELOPOULOS N, GERMENIS A, ZINTZARAS E, GOURGOULIANIS K. Morning levels of fibrinogen in children with sleep-disordered breathing. European Respiratory Journal 2004, 24:790-797
29. KADITIS AG, ALEXOPOULOS, EI, KALAMPOUKA E, KOSTADIMA E, GERMENIS AE, ZINTZARAS E, GOURGOULIANIS K. Morning levels of C-reactive protein in children with obstructive sleep-disordered breathing. American Journal of Respiratory and Critical Care Medicine 2005, 171:282-286


30. MITROULIS I, KOURTZELIS I, PAPADOPOULOS VP, MIMIDIS K, SPELETAS M, RITIS K. In vivo induction of the autophagic machinery in human bone marrow cells during Leishmania donovani complex infection. Parasitology International 2009, 58:475-477 (case report)
31. SPELETAS M, KALALA F, PAPADOPOULOS VP, MERENTITI V, MITROULIS I, RITIS K, GERMENIS AE. TLR2 and TLR4 polymorphisms in familial Mediterranean fever. Human Immunology 2009, 70:750-753
32. SPELETAS M. The emerging link between innate immunity and thrombosis. Pathophysiology of Haemostasis and Thrombosis 2008, 36(Suppl.):P52-P54 (review)
33. RAFAIL S, RITIS K, SCHAEFER K, KOURTZELIS I, SPELETAS M, DOUMAS M, GIAGLIS S, KAMBAS K, KONSTANTINIDES S, KARTALIS G. Leptin induces the expression of functional tissue factor in human neutrophils and peripheral blood mononuclear cells through JAK2-dependent mechanisms and TNF-α involvement. Thrombosis Research 2008, 122:366-375
34. GIAGLIS S, PAPADOPOULOS V, KAMBAS K, DOUMAS M, TSIRONIDOU V, RAFAIL S, KARTALIS G, SPELETAS M, RITIS K. MEFV alterations and population genetics analysis in a large cohort of Greek patients with familial Mediterranean fever. Clinical Genetics 2007, 71:458-467
35. ZOGRAFOS TA, LIASKOS C, RIGOPOULOU EI, TOGOUSIDIS E, MAKARITSIS K, GERMENIS A, DALEKOS GN. Adiponectin: a new independent predictor of liver steatosis and response to IFN-α treatment in chronic hepatitis C? American Journal of Gastroenterology 2007, 102:1-10
36. ZOGRAFOS TA, LIASKOS C, TOGOUSIDIS E, ZACHOU K, GATSELIS N, RIGOPOULOU E, GERMENIS AE, DALEKOS GN. Alterations of leptin levels during IFN-α treatment in patients with chronic viral hepatitis B and C. Journal of Hepatology 2006, 44:848-855
37. STEFANOU N, SATRA M, PAPANIKOLAOU V, KALALA F, GATSELIS N, GERMENIS AE, DALEKOS GN, TSEZOU A. Leptin receptor isoforms mRNA expression in peripheral blood mononuclear cells from patients with chronic viral hepatitis. Experimental Biology and Medicine 2006, 231:1653-1663
38. MASTELLOS D, GERMENIS AE, LAMBRIS JD. Complement: An inflammatory pathway fulfilling multiple roles at the interface of innate immunity and development. Current Drug Targets - Inflammation and Allergy 2005, 4:125-127 (invited review)


39. ALEXIOU I, GERMENIS A, KOUTROUMPAS A, KONTOGIANNI A, THEODORIDOU K, SAKKAS LI. Anti-cyclic citrullinated peptide-2 (CCP2) autoantibodies and extra articular manifestations in Greek patients with rheumatoid arthritis. Clinical Rheumatology 2008, 27:511-513
40. SAKKAS LI, BOULBOU M, KYRIAKOU D, MAKRI I, SINANI C, GERMENIS A, STATHAKIS N. Immunological features of visceral leishmaniasis may mimic systemic lupus erythematosus. Clinical Biochemistry 2008, 41:65-68
41. ROKA V, POTAMIANOS S, KAPSORITAKIS AN, YIANNAKI EE, KOUKOULIS GN, KOUKOULIS GK, GERMENIS AE. Prevalence of celiac disease in adult population of Central Greece. European Journal of Gastroenterology and Hepatology 2007, 19:982-987
42. ALEXIOU I, GERMENIS A, ZIOGAS A, THEODORIDOU K, SAKKAS L. Anti-cyclic citrullinated peptide (anti-CCP) antibodies in Greek patients with rheumatoid arthritis. BMC Musculoskeletal Disorders 2007, 8:37
43. ZINTZARAS E, GERMENIS AE. Diagnostic performance of antibodies against tissue transglutaminase for the diagnosis of celiac disease: meta-analysis. Clinical and Vaccine Immunology 2006, 13:187-192
44. GERMENIS AE, YIANNAKI EE, ZACHOU K, ROKA V, BARBANIS S, LIASKOS C, ADAM K, KAPSORITAKIS AN, POTAMIANOS S, DALEKOS GN. Prevalence and clinical significance of IgA antibodies against tissue transglutaminase in patients with diverse chronic liver diseases. Clinical and Diagnostic Laboratory Immunology 2005, 12:941-948
45. YIANNAKI EE, ZINTZARAS E, ANALATOS A, THEODORIDOU C, DALEKOS GN, GERMENIS AE. Evaluation of a microsphere-based flow cytometric assay for celiac disease diagnosis. Journal of Immunoassay and Immunochemistry 2004, 25:345-357


46. THRISKOS P, ZINTZARAS E, GERMENIS AE. DHLAS: A web-based database analysis system to support HLA population studies. Computer Methods and Programs in Biomedicine 2007, 85:267-272


47. DAIOU C, CHRISTODOULOU K, XIROMERISIOU G, PANAS M, DARDIOTIS E, KLADI A, SPELETAS M, NTAIOS G, PAPADIMITRIOU A, GERMENIS A, HADJIGEORGIOU GM. Absence of aprataxin gene mutations in a Greek cohort with sporadic early onset ataxia and normal GAA triplets in frataxin gene. Neurological Sciences 2009 (in press)
48. ZACHAROULIS D, POULTSIDIS A, KATSOGRIDAKIS E, KALALA F, NAKOU M, CHATZITHEOFILOU C. Radiofrequency-assisted partial splenectomy: Histopathological and immunological assessment of the splenic remnant in a porcine model. Surgical Endoscopy 2008, 22:1309-1316
49. GERMENIS AE, PATRIKIDOU A. Proteomics challenging medicine. Haema 2005, 8:183-192 (review)
50. BOULBOU MS, KOUKOULIS G, MAKRI E, PETINAKI E, GOURGOULIANIS K, GERMENIS A. Circulating adhesion molecules levels in type 2 diabetes mellitus and hypertension. International Journal of Cardiology 2005, 98:39-44
51. ROUSSAKI-SCHULZE AV, ZAFIRIOU E, NIKOULIS D, KLIMI E, RALLIS E, ZINTZARAS E. Objective biophysical findings in patients with sensitive skin. Drugs under Experimental and Clinical Research 2005, 31(Suppl):17-24
52. BOULBOU MS, KOUKOULIS GN, PETINAKI EA, GERMENIS A, GOURGOULIANIS K. Soluble adhesion molecules are not involved in the development of retinopathy in type 2 diabetic patients. Acta Diabetologica 2004, 41:118–122
53. SKALKIDIS E, GERMENIS AE, PATSOPOULOS N, TRICHOPOULOS D. The impact of Greek publications on the international literature by scientific category. Archives of Hellenic Medicine 2004, 21: 472-479
54. SKALKIDIS E, GERMENIS AE, PATSOPOULOS N, TRICHOPOULOS D. The impact factor of scientific journals by broad category. Archives of Hellenic Medicine 2003, 20:88-122